One person has died following the three vehicle crash on State Highway 5 at Hamurana.
Three other people have serious injuries.
Emergency services were called to the scene at 9.16pm.
The road is closed and lengthy diversions are in place.
All motorists travelling between Tirau and Rotorua are being diverted through Putaruru and Tokoroa.
Police would like to thank motorists for their patience in advance.
Issued by the Police Media Centre