Police can now confirm that there are several fatalities following the crash near Ohakuri Road this morning.
At least one person has suffered critical injuries and a rescue helicopter has been called to the scene.
The road will be closed for an extended period, so traffic will be diverted and there will be lengthy delays.
Motorists are asked to plan their journey to avoid SH1 between Taupo and Atiamuri if at all possible.
Issued by Police Media Centre