Emergency services are responding to a crash on State Highway 3, north of Whanganui.
The crash took place shortly before 1.40pm and involved two vehicles.
A number of people have sustained injuries - initial reports are that one person has critical injuries, two people have serious injuries and three people have moderate injuries.
One of the injured is understood to be trapped in a vehicle.
More information will be released as it becomes available.
ENDS
Issued by Police Media Centre.